Proton Pump Inhibitor
Proton pump inhibitor is the final step of controlling gastric acid secretion.
PPI inhibits Hidrogen pottassium adenosine triphospate enzyme which is known as proton pump of parietal cell of stomach. This enzyme promotes secretion of hydrogen ion in gastric lumen and therefore produces hydrocloric acid. By inhibiting this enzyme PPI inhibits gastric acid production.
Some common example of PPI is
Omeprazole
Esomeprazole
Lansoprazole
Rabeprazole
Pantoprazole
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